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COLIGYL 3MIU INJECTION contains colistin, which belongs to the group of medicines called Antibiotics. It is used to manage certain forms of serious bacterial infections when other antibiotics are not suitable. It is clinically effective in managing various infections caused by certain gram-negative bacteria, such as Aerobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa.

A bacterial infection can be defined as a proliferation of various harmful strains of bacteria in the body. They can affect any part(s) of the body, including the respiratory tract, urinary tract, eyes, ears, skin, soft tissue, or bones.

Colistin is a polypeptide antibiotic. It binds to the susceptible bacteria and disrupts the composition (lipids and proteins) of the bacterial cell membrane. As a result, it makes the contents of the bacterial cell leak out, which subsequently leads to bacterial killing. It may also inactivate the toxins produced by the bacteria.

Before receiving COLIGYL 3MIU INJECTION, inform your doctor if you have any kidney problems. To avoid side effects, your doctor would prescribe a low dose of colistin and constantly monitor your kidney functions while receiving COLIGYL 3MIU INJECTION. You must also inform your doctor if you have any inherited blood or muscle disorders before receiving COLIGYL 3MIU INJECTION.

Do not take COLIGYL 3MIU INJECTION if you are allergic to any of the ingredients present in it. COLIGYL 3MIU INJECTION should be used in pregnant or breastfeeding women only if prescribed by the physician. The most common side effects of receiving COLIGYL 3MIU INJECTION are stomach upset, tingling sensation in the extremities, loss of sensation, fever, or dizziness. Contact your doctor if any of these side effects worsen.

Uses Of COLIGYL 3MIU INJECTION

Manages serious bacterial infections

How COLIGYL 3MIU INJECTION Works

COLIGYL 3MIU INJECTION kills the susceptible bacteria that causes infection. It acts by disrupting the composition (lipids and proteins) of the bacterial cell membrane and enters the bacterial cell. This causes the contents of the bacterial cell to leak out, which subsequently leads to bacterial killing. It may also inactivate the effects of toxins produced by the harmful bacteria.

How to use COLIGYL 3MIU INJECTION

COLIGYL 3MIU INJECTION will be given to you only by a doctor or nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight, and severity of infection.

Side Effects Of COLIGYL 3MIU INJECTION

Common

Stomach upset

Tingling sensation in the extremities or in the tongue

Paraesthesia (loss of sensation)

Dizziness

Skin rash, itching

Fever

Breathing difficulty

Increased kidney enzymes

Rare

Contact your doctor immediately if you experience any of the following side effects after receiving COLIGYL 3MIU INJECTION:

Severe allergic reaction (such as skin rash, itching, or sudden swelling of the face, throat, or lips leading to wheezing or breathing difficulties)

Inability to breathe because of paralysis of the chest muscles, sense of tingling or numbness, especially around the face, feeling dizzy, loss of balance, rapid changes in blood pressure or blood flow causing flushing or fainting, problems in speech, problems with vision, confusion, and mental problems (including loss of sense of reality)

Kidney damage with symptoms such as little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath

How To Manage Side Effects

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely if you feel dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Skin rash Or Itching

Avoid taking hot showers, as it may further irritate your skin. Use protective clothes while going outdoors. Avoid scratching the affected area of the skin. Regularly moisturize your skin. Consult your doctor if your condition worsens.

Warning & Precautions

Pregnancy

Monitoring required

COLIGYL 3MIU INJECTION should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before receiving it.