Gerzone 1.5 Gm Injection

GERZONE INJECTION is a combination of Cefoperazone and Sulbactam, which belongs to the group of medicines called Antibiotics. It is used to manage various bacterial infections such as respiratory tract infections, urinary tract infections (upper and lower), intra-abdominal infections, septicaemia (serious bloodstream infection), meningitis (inflammation of brain and spinal cord membranes, typically caused by an infection), and skin and soft tissue infections.

It is also used to manage bone and joint infections, gonorrhoea (sexually transmitted bacterial infection), endometritis (inflammation of the uterine lining due to infection), pelvic inflammatory disease (infection of the female reproductive organs), and other infections of the genital tract.

Bacterial infections are caused by the multiplication of specific harmful strains of bacteria anywhere in the body. It is characterized by symptoms such as fever, nausea, vomiting, headache, tiredness, and swollen lymph nodes in the neck, armpits, groin, or elsewhere.

Before receiving GERZONE INJECTION, inform your doctor if you have impaired kidney function, severe biliary obstruction (blockage of the bile ducts), severe liver disease, or malabsorption conditions, and have a schedule for laboratory tests (such as measuring glucose in the urine).

GERZONE INJECTION should be used with caution in pregnant and breastfeeding women only if advised by the doctor. Also, it should be used with caution in children and elderly patients.

The most common side effects of receiving GERZONE INJECTION are diarrhea, nausea, and vomiting. Inform your doctor if any of these side effects bother you.

Uses Of GERZONE INJECTION

Manages bacterial infections such as:

• Respiratory tract infections
• Urinary tract infections (upper and lower)
• Intra-abdominal infections
• Septicaemia
• Meningitis
• Skin and soft tissue infections
• Bone and joint infections
• Pelvic inflammatory disease
• Endometritis
• Gonorrhoea
• Other infections of the genital tract

How GERZONE INJECTION Works

GERZONE INJECTION contains cefoperazone and sulbactam. Cefoperazone works by stopping the formation of bacterial cell coverings, which makes the bacteria susceptible to killing. Sulbactam works by reducing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, they help to manage various bacterial infections.

How to use GERZONE INJECTION

GERZONE INJECTION will be given to you only by a doctor or a nurse, either into the vein (intravenously) or muscle (intramuscularly). Your doctor will decide the correct dose and duration for you depending upon your age, body weight, and severity of the infection.

Side Effects Of GERZONE INJECTION

How To Manage Side Effects

Diarrhea

Keep yourself hydrated by drinking lots of fluids, such as water or fruit juices. If the symptom does not improve, inform your doctor.

Headache

Apply a hot or cold water bag to your head. Drink plenty of fluids. Try taking rest in a quiet and dark room. Apply pain-relieving balm on your forehead if necessary. Inform your doctor if the headache does not reduce.

Nausea And Vomiting

Take regular sips of cold drinks. Stick to simple meals. Avoid eating oily, fried, or spicy foods. Do not lie down or sleep immediately after eating. If nausea does not improve, inform your doctor.

Warning & Precautions

Pregnancy

Monitoring required

GERZONE INJECTION should be used during pregnancy only if considered clearly necessary. Consult your doctor before receiving GERZONE INJECTION.

Breastfeeding

Use with Caution

GERZONE INJECTION should be used with caution in breast-feeding women, as a small amount of this medicine is excreted in the breast milk. Consult your doctor before receiving GERZONE INJECTION.

Driving and Using Machines

Safe

GERZONE INJECTION does not affect your ability to drive or use machinery.

Alcohol

Contraindicated

Avoid consuming alcohol while receiving GERZONE INJECTION because it may cause flushing, sweating, headaches, and an increase in the heartbeat.

Kidney

Use with Caution

GERZONE INJECTION should be used with caution in patients with impaired kidney function. Consult your doctor before receiving GERZONE INJECTION.

Liver

Use with Caution

GERZONE INJECTION should be used with caution in patients with severe biliary obstruction (blockage of the bile ducts) and severe liver disease. Consult your doctor before receiving GERZONE INJECTION.

Allergy

Contraindicated

Do not receive GERZONE INJECTION if you are allergic to cefoperazone, sulbactam, beta-lactam antibiotics (such as Penicillins and cephalosporins (Ex. cefuroxime)) or any other ingredients of this medicine.

Use In Pediatrics

Use with Caution

GERZONE INJECTION should be used with caution in children. Your child’s doctor may adjust the dose depending upon the child's body weight. Consult your child’s doctor for advice.

Use In Geriatrics

Use with Caution

GERZONE INJECTION should be used with caution in elderly patients. Consult your doctor before receiving it.

Interactions

A. Drug-Drug interactions:

Before receiving GERZONE INJECTION, inform your doctor if you are taking any of the following medicines:

• Medicines used to manage bacterial infections, such as aminoglycosides (Ex. gentamicin, tobramycin, amikacin, and streptomycin)
• Oral anti-coagulants (Ex. warfarin) (used to manage or manage blood clots)

Overdosage:

GERZONE INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor if you experience any unusual symptoms, such as neurologic effects (such as fits).